Clidinium bromide ( Ro 2-3773 )

Catalog No. M14193 CAS No. 3485-62-9

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Product Name

Clidinium bromide
Note

Research use only, not for human use.
Brief Description

Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Description

Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.
Synonyms

Ro 2-3773
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

mAChR
Research Area

Neurological Disease
Indication

——

CAS Number

3485-62-9
Formula Weight

432.35
Molecular Formula

C22H26BrNO3
Purity

>98%(HPLC)
Solubility

DMSO: 10 mM
SMILES

C[N+]12CCC(CC1)C(C2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.[Br-]
Chemical Name

(1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide

1.Pathak A, et al. J Chromatogr Sci. 2010 Mar;48(3):235-9.

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